论文标题
{\ it Escherichia coli}的跑步动力学的表征和控制
Characterization and Control of the Run-and-Tumble Dynamics of {\it Escherichia Coli}
论文作者
论文摘要
我们使用更新过程来分析中间散射功能的测量值，表征了游泳{\ IT大肠杆菌} {\ IT大肠杆菌}种群的完整时空步态。这使我们能够定量地证明如何通过化学诱导剂控制工程菌株的持久性长度，并报告从永久性翻滚到平滑游泳的受控过渡。对于野生型{\ it E.〜大肠杆菌}，我们同时测量了微观运动参数和大尺度有效扩散率，因此首次定量桥接小规模的定向游泳和宏观扩散。
We characterize the full spatiotemporal gait of populations of swimming {\it Escherichia coli} using renewal processes to analyze the measurements of intermediate scattering functions. This allows us to demonstrate quantitatively how the persistence length of an engineered strain can be controlled by a chemical inducer and to report a controlled transition from perpetual tumbling to smooth swimming. For wild-type {\it E.~coli}, we measure simultaneously the microscopic motility parameters and the large-scale effective diffusivity, hence quantitatively bridging for the first time small-scale directed swimming and macroscopic diffusion.
