论文标题
CLRP Monte Carlo TG-43参数数据库的更新,用于高能量近距离放射治疗来源
Update of the CLRP Monte Carlo TG-43 parameter database for high-energy brachytherapy sources
论文作者
论文摘要
目的:更新和扩展了Carleton放射疗法物理学实验室(CLRP)TG-43剂量测定数据库(CLRP_TG43V2)的第2版,用于33个高能量(He,$ \ geq50 $ 〜keV)hearterape rachytheraption brachyther Paperces,使用EGS_BRACHY,使用EGS_BRACHY,一个开放式EGSNRC EGSNRC。汇编了TG-43参数的全面数据集,包括详细的源描述,剂量率常数,径向剂量功能,1D和2D各向异性函数,沿范围的剂量率表,初级和散射分离的(PSS)剂量表,以及平均光子能量,平均光子能量。数据库还记录了将与EGS_BRACHY自由分发的源模型。采集和验证方法:数据集是在使用EGS ++几何包及其EGS_BRACHY扩展的重新编码后计算数据集的。在10x10x0.05 cm3体素中计算出空气kerma,沿横轴距源为100 cm,然后校正得分素的横向和厚度尺寸,从而使中央轴上的空气kerma在100cm的中心轴上从源中间的中间点处提供。在圆柱坐标中具有不同体素分辨率的全碎片水幻像用于剂量计算。为了进行验证,将数据与CLRP_TG43V1和已发布数据的数据进行比较。数据格式和访问:可在https://physics.carleton.ca/clrp/egs_brachy/seed_database_hdrv2或http://doi.org/10.22215/clrp/clrp/clrp/tg43v2上获得。潜在应用:CLRP_TG43V2数据库在研究,剂量测定和近距离治疗计划中具有应用。这项综合更新为医学物理界提供了更精确的更精确的,在某些情况下,更准确的Monte Carlo TG-43剂量计算参数,以及用EGS_BRACHY分发的完全基准测试和描述的源模型。
PURPOSE: To update and extend version 2 of the Carleton Laboratory for Radiotherapy Physics (CLRP) TG-43 dosimetry database (CLRP_TG43v2) for 33 high-energy (HE, $\geq50$~keV) brachytherapy sources using egs_brachy, an open-source EGSnrc application. A comprehensive dataset of TG-43 parameters is compiled, including detailed source descriptions, dose-rate constants, radial dose functions, 1D and 2D anisotropy functions, along-away dose-rate tables, Primary and Scatter Separated (PSS) dose tables, and mean photon energies escaping each source. The database also documents the source models which will be freely distributed with egs_brachy. ACQUISITION AND VALIDATION METHODS: Datasets are calculated after a recoding of the source geometries using the egs++ geometry package and its egs_brachy extensions. Air kerma per history is calculated in a 10x10x0.05 cm3 voxel located 100 cm from the source along the transverse axis and then corrected for the lateral and thickness dimensions of the scoring voxel to give the air kerma on the central axis at a point 100cm from the source's mid-point. Full-scatter water phantoms with varying voxel resolutions in cylindrical coordinates are used for dose calculations. For validation, data are compared to those from CLRP_TG43v1 and published data. DATA FORMAT AND ACCESS: Data are available at https://physics.carleton.ca/clrp/egs_brachy/seed_database_HDRv2 or http://doi.org/10.22215/clrp/tg43v2. POTENTIAL APPLICATIONS: The CLRP_TG43v2 database has applications in research, dosimetry, and brachytherapy planning. This comprehensive update provides the medical physics community with more precise and in some cases more accurate Monte Carlo TG-43 dose calculation parameters, as well as fully benchmarked and described source models which are distributed with egs_brachy.