论文标题
通过价值函数替代的动态处理制度表征，并应用部分合规性
Dynamic treatment regime characterization via value function surrogate with an application to partial compliance
论文作者
论文摘要
精密医学是为了改善健康和医疗保健的证据而有前途的框架。然而，在现实世界中临床环境中的证据生成和实施的统计精确医学策略数量不断增长与缩小此差距的策略可能取决于上下文。在本文中，我们考虑了外周动脉疾病患者中部分遵守伤口管理的特定背景。通过使用高斯工艺为价值函数替代，我们超越了学习最佳动态治疗方案的常见精度医学任务，以表征动态治疗方案的类别以及如何将这些发现转化为临床环境。
Precision medicine is a promising framework for generating evidence to improve health and health care. Yet, a gap persists between the ever-growing number of statistical precision medicine strategies for evidence generation and implementation in real world clinical settings, and the strategies for closing this gap will likely be context dependent. In this paper, we consider the specific context of partial compliance to wound management among patients with peripheral artery disease. Through the use of a Gaussian process surrogate for the value function, we expand beyond the common precision medicine task of learning an optimal dynamic treatment regime to characterization of classes of dynamic treatment regimes and how those findings can be translated into clinical contexts.
