论文标题

用2.9μm激光在水中进行的无血浆气泡空化,用于生物打印应用

Plasma free bubble cavitation in water by a 2.9 μm laser for bioprinting applications

论文作者

Mohajan, Shubho, Delagnes, Jean-Christophe, Allisy, Baptiste, Iazzolino, Antonio, Viellerobe, Bertrand, Petit, Stéphane

论文摘要

我们研究了由2.9μmMID-IR激光脉冲(10 ns,10-50μJ)诱导的气泡气泡的动力学,导致由于强烈的振动吸收而导致血浆无血浆直接加热水。我们建立了激光通量(最高6 j/cm^2)和最大气泡半径(最大200μm)之间的直接相关性。从实验数据中,可以通过包括2.9μm的吸水吸收饱和度在内的模拟来检索关键参数(阈值,内部压力)。在6 j/cm^2的腔内,我们获得了转换为气泡能量的激光能量的13%,我们可以预测,在较高的通风率> 10 J/cm^2下运行将导致最高20%的转化效率。这结果使用激光辐射直接吸收生物打印应用打开了无需任何其他吸收器的范围。

We investigate the dynamics of the cavitation bubble induced by 2.9 μm mid-IR laser pulses (10 ns, 10-50 μJ) resulting in a plasma-free direct fast heating of water due to a strong vibrational absorption. We establish a direct correlation between the laser fluence (up to 6 J/cm^2) and the maximum bubble radius (up to 200 μm). From experimental data, key parameters (threshold energy, internal pressure) can be retrieved by simulations including the water absorption saturation at 2.9 μm. At a fluence of 6 J/cm^2, we obtain 13 % of the laser energy converted to a bubble energy and we can predict that operating at higher fluence >10 J/cm^2 will lead to a maximum of 20 % conversion efficiency. This results open the door to bioprinting applications using direct absorption of the laser radiation without any additional absorber.

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