论文标题
在单链纳米颗粒中设计增强的熵结合
Designing enhanced entropy binding in single-chain nano particles
论文作者
论文摘要
单链纳米颗粒（SCNP）是一类新的生物和软性聚合物对象，其中一小部分单体能够形成等效性内或间侧聚合物键。在这里，我们从数字上表明，在SCNP系统中可以进行全面的气体液相分离。可以通过明智地设计出对聚合物相互结合以形成（完全键入）聚合物网络的聚合物对不连续（一阶）变化的控制 - 从独立的稀释（完全键入）聚合物到一个阶段。这种敏感性来自控制结合的不同熵贡献之间的微妙平衡。
Single-chain nanoparticles (SCNP) are a new class of bio and soft-matter polymeric objects in which a fraction of the monomers are able to form equivalently intra- or inter-polymer bonds. Here we numerically show that a fully-entropic gas-liquid phase separation can take place in SCNP systems. Control over the discontinuous (first-order) change -- from a phase of independent diluted (fully-bonded) polymers to a phase in which polymers entropically bind to each other to form a (fully-bonded) polymer network -- can be achieved by a judicious design of the patterns of reactive monomers along the polymer chain. Such a sensitivity arises from a delicate balance between the distinct entropic contributions controlling the binding.
