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We discuss electroweak baryogenesis in aligned two Higgs doublet models. It is known that in this model the severe constraint from the experimental results for the electron electric dipole moment can be avoided by destructive interference among CP-violating effects in the Higgs sector. In our previous work, we showed that the observed baryon number in the Universe can be explained without contradicting current available data in a specific scenario in the same model. We here first discuss details of the evaluation of baryon number based on the WKB method taking into account all order of the wall velocity. We then investigate parameter spaces which are allowed under the current available data from collider, flavor and electric dipole moment experiments simultaneously. We find several benchmark scenarios which can explain baryon asymmetry of the Universe. We also discuss how we can test these benchmark scenarios at future collider experiments, various flavor experiments and gravitational wave observations.