论文标题

基于tikhonov正则化的近场X射线全息图中非线性和约束相的快速算法

Fast algorithms for nonlinear and constrained phase retrieval in near-field X-ray holography based on Tikhonov regularization

论文作者

Huhn, Simon, Lohse, Leon Merten, Lucht, Jens, Salditt, Tim

论文摘要

基于相位检索,无透镜相干成像,尤其是全息图提供了定量相和振幅图像。对于光谱范围充满挑战的光谱范围,例如硬X射线,这一点尤其重要。在这里,我们提出了一种基于Tikhonov正则化的内联X射线全息图的相位检索方法,该方法应用于图像形成的完整非线性正向模型。该方法可以看作是良好的对比转移功能(CTF)重建方法的非线性概括。尽管以前提出了类似的方法,但当前的工作在竞争计算时间上实现了非线性,被限制的相位检索。因此,我们可以对CTF范围之外的光学强度对象进行高通量成像。使用X射线波导源从照明获得的内联全息图的不同示例,即使对于不遵守弱变化阶段的假设的样品,我们也证明了出色的图像质量。由于提出的方法不依赖于线性化,因此我们希望它也非常适合其他探针,例如可见光或电子,这些探针通常表现出强相互作用。

Based on phase retrieval, lensless coherent imaging and in particular holography offers quantitative phase and amplitude images. This is of particular importance for spectral ranges where suitable lenses are challenging, such as for hard x-rays. Here, we propose a phase retrieval approach for inline x-ray holography based on Tikhonov regularization applied to the full nonlinear forward model of image formation. The approach can be seen as a nonlinear generalization of the well-established contrast-transfer-function (CTF) reconstruction method. While similar methods have been proposed before, the current work achieves nonlinear, constrained phase retrieval at competitive computation times. We thus enable high-throughput imaging of optically strong objects beyond the scope of CTF. Using different examples of inline holograms obtained from illumination by a x-ray waveguide-source, we demonstrate superior image quality even for samples which do not obey the assumption of a weakly varying phase. Since the presented approach does not rely on linearization, we expect it to be well suited also for other probes such as visible light or electrons, which often exhibit strong phase interaction.

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