论文标题
多轴场通过保留氢化物订单来提高剑术效率
Multiaxial fields improve SABRE efficiency by preserving hydride order
论文作者
论文摘要
通过可逆交换（SABER）和异核变体X-Sbre的信号扩增，使用源自para-Hydrogen的可逆结合得出的顺序提高了磁共振技术的灵敏度。军刀的一个当前局限性是在整个复合物的寿命中次优化转移。在这里，我们演示了一个多边形的低场脉冲序列，该脉冲允许在低场进化脉冲期间进行最佳的极化堆积，然后进行高视野混合脉冲，该脉冲允许沿正交轴质子解耦。这保留了偏anyrydrides的单线特征，同时允许交换补充虹膜催化剂上的配体。该策略在实验上导致对连续板剑鞘的2.5倍改进，并通过数值模拟证实。
Signal Amplification By Reversible Exchange (SABRE) and the heteronuclear variant, X-SABRE, increase the sensitivity of magnetic resonance techniques using order derived from reversible binding of para-hydrogen. One current limitations of SABRE is suboptimal polarization transfer over the lifetime of the complex. Here, we demonstrate a multiaxial low-field pulse sequence which allows optimal polarization build-up during a low-field evolution pulse, followed by a high-field mixing pulse which permits proton decoupling along an orthogonal axis. This preserves the singlet character of the parahydrides while allowing exchange to replenish the ligands on the iridium catalyst. This strategy leads to a 2.5-fold improvement over continuous field SABRE SHEATH experimentally which was confirmed with numerical simulation.
