论文标题
透视嗅觉测试期间膜片运动的定量分析以帮助诊断半脑瘫痪
Quantitative analysis of diaphragm motion during fluoroscopic sniff test to assist in diagnosis of hemidiaphragm paralysis
论文作者
论文摘要
当前用于检测悖论性隔膜运动和诊断半脑瘫痪的金标准是进行荧光镜检查测试。这些图像由经验丰富的放射科医生在视觉上检查，如果一个半脑升高，而另一个半肌则下降，则被描述为矛盾的运动，这强烈暗示了半脑瘫痪。但是，诊断可能是具有挑战性的，因为嗅探过程中的隔膜运动很快，矛盾的运动可能是微妙的，并且分析基于三维表面的二维投影。本文提出了一例慢性左半肾上腺升高的病例，最初据报道是荧光镜检查中的轻度矛盾运动。在测量隔膜的升高并使用高斯过程回归对其时间相关性进行建模之后，确定了半脑运动的系统趋势及其随机特性。在分析半脑的轨迹时，未检测到统计学上显着的矛盾运动。如果患者要将隔膜膜视为治疗，这可能会改变预后。提出的方法提供了对半脑运动运动的更客观分析，并有可能提高诊断准确性。
The current imaging gold standard for detecting paradoxical diaphragm motion and diagnosing hemidiaphragm paralysis is to perform the fluoroscopic sniff test. The images are visually examined by an experienced radiologist, and if one hemidiaphragm ascends while the other descends, then it is described as paradoxical motion, which is highly suggestive of hemidiaphragm paralysis. However, diagnosis can be challenging because diaphragm motion during sniffing is fast, paradoxical motion can be subtle, and the analysis is based on a 2-dimensional projection of a 3-dimensional surface. This paper presents a case of chronic left hemidiaphragm elevation that was initially reported as mild paradoxical motion on fluoroscopy. After measuring the elevations of the diaphragms and modeling their temporal correlation using Gaussian process regression, the systematic trend of the hemidiaphragmatic motion along with its stochastic properties was determined. When analyzing the trajectories of the hemidiaphragms, no statistically significant paradoxical motion was detected. This could potentially change the prognosis if the patient was to consider diaphragm plication as treatment. The presented method provides a more objective analysis of hemidiaphragm motions and can potentially improve diagnostic accuracy.
