论文标题
部分可观测时空混沌系统的无模型预测
SleepPPG-Net: a deep learning algorithm for robust sleep staging from continuous photoplethysmography
论文作者
论文摘要
简介:睡眠分期是诊断睡眠障碍和睡眠健康管理的重要组成部分。传统上是在临床环境中测量的,需要劳动密集型的标签过程。我们假设可以使用原始光摄影学(PPG)时间序列和深度学习的现代进步(DL)进行健壮的4级睡眠分期。方法:我们使用了两个公开可用的睡眠数据库,其中包括原始PPG记录,总计2,374例患者和23,055小时。我们开发了SleePPPG-NET,这是一种DL模型,用于从原始PPG时间序列中进行4级睡眠阶段。 SleePPPG-NET经过端对端训练,由一个用于自动特征提取的残留卷积网络和一个时间卷积网络,以捕获长距离上下文信息。我们基于基于报告最佳的最新算法(SOTA)算法对SleePPPG-NET的性能进行了基准测试。结果:当在持有的测试集上进行基准测试时,SleepppPG-NET获得了Cohen的Kappa中位数($κ$)得分为0.75,而最佳SOTA方法为0.69。 SleePPPG-NET对外部数据库表现出良好的概括性性能,在转移学习后获得了0.74的$κ$得分。透视图:总体而言,SleePPPG-NET提供了新的SOTA性能。此外,性能足够高,可以为满足临床应用中使用要求(例如诊断和监测阻塞性睡眠呼吸暂停的临床应用要求)的需求开发道路。
Introduction: Sleep staging is an essential component in the diagnosis of sleep disorders and management of sleep health. It is traditionally measured in a clinical setting and requires a labor-intensive labeling process. We hypothesize that it is possible to perform robust 4-class sleep staging using the raw photoplethysmography (PPG) time series and modern advances in deep learning (DL). Methods: We used two publicly available sleep databases that included raw PPG recordings, totalling 2,374 patients and 23,055 hours. We developed SleepPPG-Net, a DL model for 4-class sleep staging from the raw PPG time series. SleepPPG-Net was trained end-to-end and consists of a residual convolutional network for automatic feature extraction and a temporal convolutional network to capture long-range contextual information. We benchmarked the performance of SleepPPG-Net against models based on the best-reported state-of-the-art (SOTA) algorithms. Results: When benchmarked on a held-out test set, SleepPPG-Net obtained a median Cohen's Kappa ($κ$) score of 0.75 against 0.69 for the best SOTA approach. SleepPPG-Net showed good generalization performance to an external database, obtaining a $κ$ score of 0.74 after transfer learning. Perspective: Overall, SleepPPG-Net provides new SOTA performance. In addition, performance is high enough to open the path to the development of wearables that meet the requirements for usage in clinical applications such as the diagnosis and monitoring of obstructive sleep apnea.