论文标题
使用石墨烯以外的二维材料的DNA碱基检测
DNA Base Detection Using Two-Dimensional Materials Beyond Graphene
论文作者
论文摘要
石墨烯对纳米孔DNA测序的成功表明，可以探索除石墨烯之外的2D材料的其他潜在的单原子层和几层厚的层，并且这些材料也可以表现出对DNA碱基检测的引人入胜且具有技术有用的特性，而DNA碱基检测则优于石墨烯。在本文中，我们使用石墨烯以外的2D材料回顾了DNA碱基检测的最新技术。最初，我们介绍了使用生物和固态纳米孔的基于纳米孔的DNA测序方法的概述，并讨论了一些挑战，这些挑战限制了它们用于单基碱基分辨率的挑战。然后，我们概述了使用石墨烯的进度，挑战和机会。此外，我们讨论了除石墨烯之外的几种潜在的2D材料，例如六角硼，石墨烯以外的元素2D材料和2D过渡金属二分法。最后，我们强调了将范德华材料用于晚期DNA碱基检测技术的潜力。
The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single- and few-atom thick layers of 2D materials beyond graphene, and also that these materials can exhibit fascinating and technologically useful properties for DNA base detection that are superior to those of graphene. In this article, we review the state-of-the art of DNA base detection using 2D materials beyond graphene. Initially, we present an overview of nanopore-based DNA sequencing methods using biological and solid-state nanopores, and discuss several challenges that limit their use for single-base resolution. Then we outline the progress, challenges, and opportunities using graphene. Additionally, we discuss several potential 2D materials beyond graphene such as hexagonal boron nitride, elemental 2D materials beyond graphene, and 2D transition metal dichalcogenides. Finally, we highlight the potential of using van der Waals materials for advanced DNA base detection technologies.
