论文标题
在体外评估Ceftiofur钠和新的硫酸乙醇素配方对Marek疾病病毒生存能力的影响
In vitro evaluation of the effect of Ceftiofur Sodium and of a new Gentamycin Sulfate formulation on the viability of Marek disease virus
论文作者
论文摘要
本研究评估了硫酸庆大霉素和ceftiofur钠对Marek病毒的可行性的体外作用。当与50 mg/ml硫酸庆大霉素或Ceftiofur钠一起孵育时，与细胞相关的火鸡疱疹病毒（HVT）疫苗的滴度并未明显降低。在重新建立疫苗后，与抗生素0、15、30和60分钟相关的重构疫苗的斑块形成单位数量（PFU）之间没有发现统计差异。抗生素并未大大改变pH值。当疫苗重建后30分钟和60分钟接种时，所有疫苗溶液的滴度都有显着降低。然而，这些滴度高于预防马雷克疾病所需的滴度。
The present study evaluated In vitro effect of gentamicin sulfate and ceftiofur sodium on the viability of the Marek's disease virus. The titer of cell associated turkey herpesvirus (HVT) vaccine was not appreciably reduced when incubated with 50 mg/ml of gentamicin sulfate or ceftiofur sodium. Statistic difference was not found between the number of plaqueforming units (PFU) of reconstituted vaccine associated with both antibiotics 0, 15, 30 and 60 minutes after reconstitution of vaccine. The antibiotics did not considerably alter the pH values. There was a significative decrease of the titer of all vaccinal solutions when they were inoculated 30 and 60 minutes after the reconstitution of the vaccine. Nevertheless, these titers are higher than the required titers to protectect against the Marek disease.
