论文标题
两种具有交叉免疫力的传染病的最佳疫苗接种计划
Optimal vaccination program for two infectious diseases with cross immunity
论文作者
论文摘要
通常有多种具有交叉免疫力的疾病争夺疫苗接种资源。在这里，我们研究了两层易感感染的（SIR）模型中的最佳疫苗接种计划，其中两种具有交叉免疫力的疾病在同一人群中扩散，并且两种疾病的疫苗都可以使用。我们确定了最佳疫苗接种计划的三种情况，该方案防止了两种疾病的爆发，以最低成本的爆发。我们通过分析得出一个标准来根据不同疫苗的成本指定最佳程序。
There are often multiple diseases with cross immunity competing for vaccination resources. Here we investigate the optimal vaccination program in a two-layer Susceptible-Infected-Removed (SIR) model, where two diseases with cross immunity spread in the same population, and vaccines for both diseases are available. We identify three scenarios of the optimal vaccination program, which prevents the outbreaks of both diseases at the minimum cost. We analytically derive a criterion to specify the optimal program based on the costs for different vaccines.
