论文标题

RNA-蛋白质颗粒的波动扩散:与热力学的类比

Fluctuating diffusivity of RNA-protein particles: Analogy with thermodynamics

论文作者

Itto, Yuichi

论文摘要

讨论了对热力学的变化扩散率的形式类比,用于使荧光NA分子荧光融合到活细胞中的蛋白质。关于这种RNA-蛋白质颗粒(如内部能量的类似物)的波动扩散的平均值,确定了热量和工作量的类似物。显示出与扩散率波动相关的熵的表明,类似于Clausius的不等式,该熵具有类似于热力学熵的作用,而热量的类似物则具有类似的热量。还从几何学角度检查了统计波动分布的变化。鉴于热力学定律,目前的讨论可能有助于更深入地了解波动的扩散率。

A formal analogy of fluctuating diffusivity to thermodynamics is discussed for messenger RNA molecules fluorescently fused to a protein in living cells. Regarding the average value of the fluctuating diffusivity of such RNA-protein particles as the analog of the internal energy, the analogs of the quantity of heat and work are identified. The Clausius-like inequality is shown to hold for the entropy associated with diffusivity fluctuations, which plays a role analogous to the thermodynamic entropy, and the analog of the quantity of heat. The change of the statistical fluctuation distribution is also examined from a geometric perspective. The present discussions may contribute to a deeper understanding of the fluctuating diffusivity in view of the laws of thermodynamics.

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