论文标题
探索诊断时间的性别差异
Exploring Gender Disparities in Time to Diagnosis
论文作者
论文摘要
基于性别和基于性别的医疗保健差异导致健康结果的差异。我们通过对29个表型和195,000名患者进行两次大规模的互补分析，重点关注诊断时间（TTD）。我们首先发现，即使出现相同的条件，女性也比男性更有可能比男性更长的TTD。我们进一步探讨了TTD差异如何通过评估越来越多的诊断信息来评估性别 - 敏锐的疾病分类器，如何影响性别跨和持续的性别之间的诊断表现。在这两种公平分析中，诊断过程都偏向男性而不是女性，这与先前的观察结果相矛盾，即女性可能比男性更早表现出相关症状。这些分析表明，在研究性别差异时，TTD是一个重要但复杂的方面，并需要进一步研究。
Sex and gender-based healthcare disparities contribute to differences in health outcomes. We focus on time to diagnosis (TTD) by conducting two large-scale, complementary analyses among men and women across 29 phenotypes and 195K patients. We first find that women are consistently more likely to experience a longer TTD than men, even when presenting with the same conditions. We further explore how TTD disparities affect diagnostic performance between genders, both across and persistent to time, by evaluating gender-agnostic disease classifiers across increasing diagnostic information. In both fairness analyses, the diagnostic process favors men over women, contradicting the previous observation that women may demonstrate relevant symptoms earlier than men. These analyses suggest that TTD is an important yet complex aspect when studying gender disparities, and warrants further investigation.
