论文标题
白血病及其治疗的数学模型：评论
Mathematical models of Leukaemia and its treatment: A review
论文作者
论文摘要
白血病约占成人诊断出的所有癌症类型的3％，是小儿儿童中最常见的癌症类型。对肿瘤学中数学模型的使用以提出推论和做出预测，对实验生物医学模型提供了互补的图片，人们对使用数学模型的兴趣越来越大。在本文中，我们概括了白血病生长动力学，时间和对治疗的反应的数学建模艺术状态。我们打算描述数学方法论，在建模中考虑的生物学方面以及每个研究的结论。这篇综述旨在为该领域的研究人员提供坚实的背景材料，以便在有前途的数学生物学领域取得进一步的突破。
Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the use of mathematical models in oncology to draw inferences and make predictions, providing a complementary picture to experimental biomedical models. In this paper we recapitulate the state of the art of mathematical modelling of leukaemia growth dynamics, in time and response to treatment. We intend to describe the mathematical methodologies, the biological aspects taken into account in the modelling, and the conclusions of each study. This review is intended to provide researchers in the field with solid background material, in order to achieve further breakthroughs in the promising field of mathematical biology.
