论文标题
生物信息
Biological Information
论文作者
论文摘要
在计算机科学中，我们可以从理论上整洁地分开信息，硬件和软件以及程序及其输入的传输和处理。尽管如此，我认为这在生物学中更为复杂，但香农的信息概念在生物学中很有用，尽管它的应用并不像许多人认为的那样简单。实际上，最近开发的信息分解理论可以大大阐明编码与监管或内部和环境信息之间的互补性。我们在这项贡献中提出的主要挑战是了解遗传信息和外部因素如何结合起来创建生物体，相反，基因组在进化过程中如何利用环境以及类似地，编码，调节和空间组织如何在细胞过程中相互作用。
In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology, Nevertheless, I argue that Shannon's concept of information is useful in biology, although its application is not as straightforward as many people think. In fact, the recently developed theory of information decomposition can shed much light on the complementarity between coding and regulatory, or internal and environmental information. The key challenge that we formulate in this contribution is to understand how genetic information and external factors combine to create an organism, and conversely, how the genome has learned in the course of evolution how to harness the environment, and analogously, how coding, regulation and spatial organization interact in cellular processes.
