论文标题
基于最佳测试量基于异质复杂网络中流行病扩散的干预策略
Optimal test-kit based intervention strategy of epidemic spreading in heterogeneous complex networks
论文作者
论文摘要
我们提出了一种确定性的传染病阶级模型,该模型将测试套作为抑制和缓解流行病的重要成分。提供了严格的模拟(带有分析论点),以揭示最终暴发大小和感染峰的有效减小,这是单个斑块中基本繁殖数的函数。此外,为了研究斑块之间长距离和短途人类迁移的影响,我们考虑了异质网络,在线性扩散连通性由网络链接结构确定。我们从数值上确认,在具有较大程度或中心中心的节点(贴片)中的测试套件可以大大降低感染的峰值(以及最终暴发大小)。提供了基于下一代基质的分析处理,以找出整个网络中的关键传输概率以开始流行病。最后,在两个真实网络中验证了最佳干预策略:印度加尔各答的全球机场网络和运输网络。
We propose a deterministic compartmental model of infectious disease which considers the test-kits as an important ingredient for the suppression and mitigation of epidemics. A rigorous simulation (with analytical argument) is provided to reveal the effective reduction of final outbreak size and peak of infection as a function of basic reproduction number in a single patch. Further, to study the impact of long and short-distance human migration among the patches, we have considered heterogeneous networks where the linear diffusive connectivity is determined by the network link structure. We numerically confirm that implementation of test-kits in the fraction of nodes (patches) having larger degrees or betweenness centralities can reduce the peak of infection (as well as final outbreak size) significantly. A next-generation matrix based analytical treatment is provided to find out the critical transmission probability in the entire network for the onset of epidemics. Finally, the optimal intervention strategy is validated in two real networks: global airport networks and transportation networks of Kolkata, India.