论文标题
多SLAT提示摄像机的远端边缘确定精度：检测系统的全面模拟和优化
Distal edge determination precision for a multi-slat promptgamma camera: a comprehensive simulation and optimization of the detection system
论文作者
论文摘要
多SLAT提示摄像机是质子治疗期间范围监测的有前途的工具。我们报告了一项综合模拟研究的结果，该研究分析了精度，该精度可以通过该摄像机确定Bragg峰远端的位置。我们首次包括光光子的模拟。质子梁（单铅笔梁，130 MeV，10 ns束周期，总计10^8质子）正在与甲基丙烯酸甲酯（PMMA）幻影相互作用，该phantom的直径和长度为200 mm。在幻影中生成的及时γ射线与多缝准直仪仪合成，并使用Yttrium铝钙钛矿（YAP）闪烁体的组合检测，并安装在准仪表仪和光传感器中。考虑了两个闪烁器填料方案，一个带有每个光圈的闪烁板。使用两种检测器优化方法确定准精度的准仪构型（隔膜厚度，孔径和高度），从而确定最佳精度。在边缘位置确定中，精度为2.1 mm（最大宽度为一半）。
Multi-slat prompt-gamma camera is a promising tool for range monitoring during proton therapy. We report the results of a comprehensive simulation study analyzing the precision which is possible to reach with this camera in determination of the position of the distal edge of the Bragg peak. For the first time we include simulation of optical photons. The proton beam (single pencil beam, 130 MeV, 10 ns bunch period, total of 10^8 protons) is interacting with a polymethyl methacrylate (PMMA) phantom, which is a cylinder of 200 mm in diameter and length. The prompt gamma rays generated in the phantom are collimated with a multi-slat collimator and detected using a combination of yttrium aluminum perovskite (YAP) scintillators, installed in the collimator apertures, and light sensors. Two scintillator packing schemes, with one and with two scintillator plates per aperture, are considered. The collimator configuration (the septal thickness, aperture and height), resulting in the best precision, is determined using two methods of detector optimization. Precision of 2.1 mm (full width at half maximum) in the edge position determination is demonstrated.
