论文标题
可调粒子通过确定性的绝对负迁移率分离
Tunable particle separation via deterministic absolute negative mobility
论文作者
论文摘要
粒子隔离技术是许多科学和工程领域的聚光灯。在食品工业中,可以在分离方案的帮助下预防有害的细菌活动。在医疗保健中,隔离技术用于区分癌症和健康细胞或阿尔茨海默氏症和帕金森氏病的治疗。我们认为,具有不同尺寸的布朗颗粒在周期性的电势中移动,并受到公正的驾驶和恒定力。当给定尺寸的颗粒以与所施加的恒定力相反的方向运输时,我们通过负迁移率的违反直觉效果揭示了有效的分离策略。我们证明了一种可调的分离解决方案,其中粒子的大小可以通过应用于系统的外力的参数的变化来控制。这种方法是迈向护理点实验室芯片设备的重要一步。
Particle isolation techniques are in the spotlight of many areas of science and engineering. In food industry, a harmful bacterial activity can be prevented with the help of separation schemes. In health care, isolation techniques are used to distinguish cancer and healthy cells or in therapy for Alzheimer's and Parkinson's diseases. We consider a cloud of Brownian particles of different sizes moving in a periodic potential and subjected to an unbiased driving as well as a constant force. We reveal an efficient separation strategy via the counterintuitive effect of negative mobility when particles of a given size are transported in a direction opposite to the applied constant force. We demonstrate a tunable separation solution in which size of the particle undergoing separation may be controlled by variation of the parameters of the external force applied to the system. This approach is an important step towards the development of point-of-care lab-on-a-chip devices.