论文标题
达尔文人的口味进化
Darwinian Evolution of Taste
论文作者
论文摘要
什么是生活。在这里讨论了Schrodingers的问题，以针对特定的蛋白质Villin，该蛋白质在检测味道和声音的组织中建立细胞。 villin由与肽骨架链结合的827个氨基酸的序列表示。我们将注意力集中在一个有限的问题上，即弗莱林序列从鸡到人类的进化。使用基于热力学域缩放的新物理学方法分析了这个生物物理问题，该方法弥合了物理概念，自组织的批判性和常规生物结构实践之间的差距。事实证明，进化变化可以通过达尔文主义的选择来解释，达尔文的选择在蛋白质水平上普遍接受。该陈述是独立的，不需要先前在分子水平上具有蛋白质的经验。
What is life. Schrodingers question is discussed here for a specific protein, villin, which builds cells in tissues that detect taste and sound. Villin is represented by a sequence of 827 amino acids bound to a peptide backbone chain. We focus attention on a limited problem, the Darwinian evolution of villin sequences from chickens to humans. This biophysical problem is analyzed using a new physicical method based on thermodynamic domain scaling, a technique that bridges the gap between physical concepts, self-organized criticality, and conventional biostructural practice. It turns out that the evolutionary changes can be explained by Darwinian selection, which is not generally accepted by biologists at the protein level. The presentation is self-contained, and requires no prior experience with proteins at the molecular level.
