论文标题

分布式优化非辅助纳米谱学

Distributed optimization for nonrigid nano-tomography

论文作者

Nikitin, Viktor, De Andrade, Vincent, Slyamov, Azat, Gould, Benjamin J., Zhang, Yuepeng, Sampathkumar, Vandana, Kasthuri, Narayanan, Gursoy, Doga, De Carlo, Francesco

论文摘要

纳米计算层析成像(Nano-CT)的分辨率水平和重建质量部分受显微镜的稳定性限制,因为扫描过程中机械振动的幅度与成像分辨率相当,以及样品在数据采集期间抵抗光束损伤的能力。在这种情况下,在不同时间步骤中恢复样本状态(如时间分辨的重建方法)没有动力,而是目标是以最高的空间分辨率检索单个重建,而没有任何成像文物。在这里,我们提出了一个联合求解器,用于在纳米级的纳米级成像样品,并进行投影比对,不明式和正则化。投影数据一致性受Farneback算法估计的密集光流的调节,从而导致样品重建较少,伪像较少。合成数据测试显示了泊松和低频背景噪声的方法的鲁棒性。该方法的适用性在两个大规模的纳米成像实验数据集上证明。

Resolution level and reconstruction quality in nano-computed tomography (nano-CT) are in part limited by the stability of microscopes, because the magnitude of mechanical vibrations during scanning becomes comparable to the imaging resolution, and the ability of the samples to resist beam damage during data acquisition. In such cases, there is no incentive in recovering the sample state at different time steps like in time-resolved reconstruction methods, but instead the goal is to retrieve a single reconstruction at the highest possible spatial resolution and without any imaging artifacts. Here we propose a joint solver for imaging samples at the nanoscale with projection alignment, unwarping and regularization. Projection data consistency is regulated by dense optical flow estimated by Farneback's algorithm, leading to sharp sample reconstructions with less artifacts. Synthetic data tests show robustness of the method to Poisson and low-frequency background noise. Applicability of the method is demonstrated on two large-scale nano-imaging experimental data sets.

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