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We use the latest multi-redshift ($z=6.5-8.7$) upper limits on the 21-cm signal from the Murchison Widefield Array (MWA) to explore astrophysical models which are inconsistent with the data. These upper limits are achieved using 298 h of carefully excised data over four observing seasons. To explore these upper limits in the context of reionisation astrophysics, we use 21CMMC. We then connect the disfavoured regions of parameter space to existing observational constraints on reionisation such as high-$z$ galaxy ultra-violet (UV) luminosity functions, background UV photoionisation rate, intergalactic medium (IGM) neutral fraction, the electron scattering optical depth and the soft-band X-ray emissivity. We find the vast majority of models disfavoured by the MWA limits are already inconsistent with existing observational constraints. These inconsistent models arise from two classes of models: (i) `cold' reionisation and (ii) pure matter density fluctuations (i.e. no reionisation). However, a small subsample of models are consistent implying the existing MWA limits provide unique information in disfavouring models of reionisation, albeit extremely weakly. We also provide the first limits on the soft-band X-ray emissivity from galaxies at high redshifts, finding $1σ$ lower limits of $ε_{{\rm X},0.5-2~{\rm keV}}\gtrsim10^{34.5}$ erg s$^{-1}$ Mpc$^{-3}$. Finally, we recover 95 per cent disfavoured limits on the IGM spin temperature of $\bar{T}_{\rm S}\lesssim$ 1.3, 1.4, 1.5, 1.8, 2.1, 2.4 K at $z=6.5, 6.8, 7.1, 7.8, 8.2, 8.7$. With this we infer the IGM must have undergone, at the very least, a small amount of X-ray heating. Note, the limits on $ε_{{\rm X},0.5-2~{\rm keV}}$ and $\bar{T}_{\rm S}$ are conditional on the IGM neutral fraction.