论文标题

巴西圣保罗市Covid-19死亡率的时空动态:将高风险从最好的风险转移到最坏的社会经济状况

Spatiotemporal dynamic of COVID-19 mortality in the city of Sao Paulo, Brazil: shifting the high risk from the best to the worst socio-economic conditions

论文作者

Bermudi, Patricia Marques Moralejo, Lorenz, Camila, de Aguiar, Breno Souza, Failla, Marcelo Antunes, Barrozo, Ligia Vizeu, Chiaravalloti-Neto, Francisco

论文摘要

目前,巴西是世界上增长最快的Covid-19世界流行病之一,到目前为止,它至少造成了9.4万确认的死亡。圣保罗市特别脆弱,因为它是该国人口最多的人。分析Covid-19的时空动力学对于帮助迫切需要更好地融合面对大流行的行为很重要。因此,这项研究旨在分析从2020年3月至2020年7月的COVID-19死亡率,考虑到巴西最居高临下的城市中的时空体系结构,人口的社会经济环境以及使用精细的颗粒状水平。为此,我们使用死亡率信息系统的二级公共数据进行了一项生态研究。我们按性别和年龄描述每个流行病学周和整个时期的死亡率。我们使用时空和时空体系结构以及泊松概率分布在潜在的高斯贝叶斯模型方法中对死亡进行了建模。我们获得了时间和时空趋势以及社会经济条件的相对风险。为了减少可能的子通知,我们考虑了已确认和可疑死亡。我们的发现表明,在该时期结束时,时间趋势明显稳定,但这可能在将来发生变化。死亡率随着年龄的增长而增加,男性较高。在整个研究期间,社会状况最差的地区的死亡风险更大。但是,随着时间的流逝,这并不是统一的模式,因为我们确定了从最佳社会经济条件到最坏情况的地区的高风险转变。我们的研究通过强调死亡风险较高的地区地理筛查的重要性,目前,社会经济环境较差,是通过综合公共卫生行动来降低疾病死亡率和健康不平等的关键方面。

Currently, Brazil has one of the fastest increasing COVID-19 epidemics in the world, that has caused at least 94 thousand confirmed deaths until now. The city of Sao Paulo is particularly vulnerable because it is the most populous in the country. Analyzing the spatiotemporal dynamics of COVID-19 is important to help the urgent need to integrate better actions to face the pandemic. Thus, this study aimed to analyze the COVID-19 mortality, from March to July 2020, considering the spatio-time architectures, the socio-economic context of the population, and using a fine granular level, in the most populous city in Brazil. For this, we conducted an ecological study, using secondary public data from the mortality information system. We describe mortality rates for each epidemiological week and the entire period by sex and age. We modelled the deaths using spatiotemporal and spatial architectures and Poisson probability distributions in a latent Gaussian Bayesian model approach. We obtained the relative risks for temporal and spatiotemporal trends and socio-economic conditions. To reduce possible sub notification, we considered the confirmed and suspected deaths. Our findings showed an apparent stabilization of the temporal trend, at the end of the period, but that may change in the future. Mortality rate increased with increasing age and was higher in men. The risk of death was greater in areas with the worst social conditions throughout the study period. However, this was not a uniform pattern over time, since we identified a shift from the high risk in the areas with best socio-economic conditions to the worst ones. Our study contributed by emphasizing the importance of geographic screening in areas with a higher risk of death, and, currently, worse socio-economic contexts, as a crucial aspect to reducing disease mortality and health inequities, through integrated public health actions.

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