论文标题

在半百万胸部X射线图像中搜索气胸

Searching for Pneumothorax in Half a Million Chest X-Ray Images

论文作者

Sze-To, Antonio, Tizhoosh, Hamid

论文摘要

气胸是一种塌陷或掉落的肺,是经验丰富的放射科医生在胸部X射线上检测到的致命状况。由于缺乏此类专家,已经开发了基于深神经网络的自动检测系统。然而,实践中应用此类系统仍然是一个挑战。这些系统主要计算出单个概率为输出,可能不足以诊断。相反,基于内容的医学图像检索(CBIR)系统(例如图像搜索)可以通过比较他们正在检查的病例与以前(已诊断)病例的案例来帮助临床医生出于诊断目的。但是,缺乏对这种尝试的研究。在这项研究中,我们探讨了图像搜索的使用将气胸对胸部X射线图像进行分类。所有胸部X射线图像首先都标有深度预审慎的特征,这些特征是从现有的深度学习模型中获得的。给定查询胸部X射线图像,然后将最高K检索图像的大多数投票用作分类器,其中在过去的情况下,除了概率输出外,还提供了过去案例档案中的类似情况。在我们的实验中,从最近发布的三个大型公共数据集获得了551,383张胸部X射线图像。使用10倍的交叉验证,与经过相同特征训练的传统分类器获得的图像搜索相比,在深度审慎的特征上获得了有希望的结果。据《最好的知识》,这是第一项研究证明,经过深思熟虑的特征可用于半百万胸部X射线图像的气胸CBIR。

Pneumothorax, a collapsed or dropped lung, is a fatal condition typically detected on a chest X-ray by an experienced radiologist. Due to shortage of such experts, automated detection systems based on deep neural networks have been developed. Nevertheless, applying such systems in practice remains a challenge. These systems, mostly compute a single probability as output, may not be enough for diagnosis. On the contrary, content-based medical image retrieval (CBIR) systems, such as image search, can assist clinicians for diagnostic purposes by enabling them to compare the case they are examining with previous (already diagnosed) cases. However, there is a lack of study on such attempt. In this study, we explored the use of image search to classify pneumothorax among chest X-ray images. All chest X-ray images were first tagged with deep pretrained features, which were obtained from existing deep learning models. Given a query chest X-ray image, the majority voting of the top K retrieved images was then used as a classifier, in which similar cases in the archive of past cases are provided besides the probability output. In our experiments, 551,383 chest X-ray images were obtained from three large recently released public datasets. Using 10-fold cross-validation, it is shown that image search on deep pretrained features achieved promising results compared to those obtained by traditional classifiers trained on the same features. To the best of knowledge, it is the first study to demonstrate that deep pretrained features can be used for CBIR of pneumothorax in half a million chest X-ray images.

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