论文标题
分层的单侧读数DOI TOF-PET检测器
A layered single-side readout DOI TOF-PET detector
论文作者
论文摘要
我们正在探索具有高灵敏度，DOI功能和定时分辨率的基于闪烁的检测器，以单侧读出配置。我们的概念结合在一起：1）具有2个以上的晶体阵列的设计，并带有相对偏移，并具有固有的DOI信息，但在常规的光共享读数时尚未显示出良好的时序性能。 2）单晶阵列与光电探测器（PD）阵列具有一对一的耦合，具有良好的定时性能，但没有doi。我们认为，交错设计的第一层与PD阵列一对一耦合可能会提供DOI和时机的组合。此概念在这里通过轻型传输模拟进行评估。结果表明：1）在DOI一对一的读数方面，第一层允许使用单个阈值相对于PD SUM信号进行精确提取，最多4层。超过阈值的PD像素数对应于相互作用层。对于相同的几何形状，使用光共享读数方案是不可能的。 2）当使用2个光学光子的低阈值时，由于晶体厚度的降低，与单层相比，第一层一对一读数的分层方法可以改善接近PD的时间。单个检测器的时序分辨率值为91、127、151和164 PS，在带有未抛光像素的4层设计中看到，而单一阵列的单一阵列为148 PS，一对一耦合。 3）对于带有光共享读数的分层设计，定时会随着PD像素大小的增加而改善，在空间分辨率和未观察到的时机之间显然取舍了一对一的耦合。直接，准确的DOI确定，良好的时机性能和相对简单的设计的结合使提出的探测器成为大脑专用DOI TOF-PET的有前途的候选者。
We are exploring a scintillator-based detector with potential of high sensitivity, DOI capability and timing resolution in a single-side readout configuration. Our concept combines: 1) A design with 2+ crystal arrays stacked with relative offset, with inherent DOI information but good timing performance has not been shown with conventional light sharing readout. 2) Single crystal array with one-to-one coupling to the photodetector (PD) array, with good timing performance, but no DOI. We believe the combination, where the first layer of a staggered design is coupled one-to-one to a PD array may provide both DOI and timing. The concept is here evaluated through light transport simulations. Results show that: 1) In terms of DOI one-to-one readout of the first layer allows for accurate DOI extraction using a single threshold relative to the PD sum signal, for up to 4 layers. The number of PD pixels exceeding the threshold corresponds to the layer of interaction. The corresponding approach is not possible for the same geometries with a light sharing readout scheme. 2) When employing a low threshold of 2 optical photons the layered approach with one-to-one readout of the first layer improves timing close to the PD compared to single layer, due to reduced crystal thickness. Single detector timing resolution values of 91, 127, 151 and 164 ps were seen in the 4-layer design with unpolished pixels, compared to 148 ps for single array with one-to-one coupling. 3) For the layered design with light sharing readout, timing improves with increased PD pixel size, with an apparent tradeoff between spatial resolution and timing not observed for the one-to-one coupled counterpart. The combination of straightforward and accurate DOI determination, good timing performance and relatively simple design makes the proposed detector a promising candidate for brain dedicated DOI TOF-PET.
