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Learning informative representations of users and items from the interaction data is of crucial importance to collaborative filtering (CF). Present embedding functions exploit user-item relationships to enrich the representations, evolving from a single user-item instance to the holistic interaction graph. Nevertheless, they largely model the relationships in a uniform manner, while neglecting the diversity of user intents on adopting the items, which could be to pass time, for interest, or shopping for others like families. Such uniform approach to model user interests easily results in suboptimal representations, failing to model diverse relationships and disentangle user intents in representations. In this work, we pay special attention to user-item relationships at the finer granularity of user intents. We hence devise a new model, Disentangled Graph Collaborative Filtering (DGCF), to disentangle these factors and yield disentangled representations. Specifically, by modeling a distribution over intents for each user-item interaction, we iteratively refine the intent-aware interaction graphs and representations. Meanwhile, we encourage independence of different intents. This leads to disentangled representations, effectively distilling information pertinent to each intent. We conduct extensive experiments on three benchmark datasets, and DGCF achieves significant improvements over several state-of-the-art models like NGCF, DisenGCN, and MacridVAE. Further analyses offer insights into the advantages of DGCF on the disentanglement of user intents and interpretability of representations. Our codes are available in https://github.com/xiangwang1223/disentangled_graph_collaborative_filtering.