论文标题

凋亡:病毒感染中的生理作用

Pyroptosis: Physiological roles in viral infection

论文作者

Duran, Nelson, Favaro, Wagner J.

论文摘要

当前的综述着重于凋亡的重要方面,例如炎性症的形态特征,以及有关冠状病毒感染机制的知识以及SARS-COV-2感染与细胞凋亡之间的关联。如今,对COVID-19患者进行免疫调节疗法的应用是最有前途的治疗方法。本研究还解决了帮助保护患者免受感染的帮助的可能性。

The current review focuses on important aspects of pyroptosis, such as morphological features of inflammasomes, as well as on knowledge about coronavirus infection mechanisms and the association between SARS-CoV-2 infection and cell pyroptosis. The application of immunomodulation therapies to Covid-19 patients is the most promising treatment under investigation nowadays. The possibilities of assistance to help protecting patients from infections are also addressed in the present study.

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