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We consider the generalized Stokes resolvent problem in an infinite layer with Neumann boundary conditions. This problem arises from a free boundary problem describing the motion of incompressible viscous one-phase fluid flow without surface tension in an infinite layer bounded both from above and from below by free surfaces. We derive a new exact solution formula to the generalized Stokes resolvent problem and prove the $\mathscr{R}$-boundedness of the solution operator families with resolvent parameter $λ$ varying in a sector $Σ_{\varepsilon,γ_0}$ for any $γ_0>0$ and $0<\varepsilon<π/2$, where $Σ_{\varepsilon,γ_0} =\{ λ\in\mathbb{C}\setminus\{0\} \mid |\argλ|\leqπ-\varepsilon, \ |λ|>γ_0 \}$. As applications, we obtain the maximal $L_p$-$L_q$ regularity for the nonstationary Stokes problem and then establish the well-posedness locally in time of the nonlinear free boundary problem mentioned above in $L_p$-$L_q$ setting. We make full use of the solution formula to take $γ_0>0$ arbitrarily, while in general domains we only know the $\mathscr{R}$-boundedness for $γ_0\gg1$ from the result by Shibata. As compared with the case of Neumann-Dirichlet boundary condition studied by Saito, analysis is even harder on account of higher singularity of the symbols in the solution formula.