论文标题
异常血小板传输和脂肪尾分布
Anomalous Platelet Transport & Fat-Tailed Distributions
论文作者
论文摘要
通常假定血小板在血液中的运输遵守对流扩散方程。在这里，我们提出了一种破坏性的观点，表明其速度的随机部分受脂肪尾概率分布的约束，通常称为Lévy飞行。尽管对于较小的时空尺度，但很难将其与普遍接受的“红细胞增强”的布朗运动区分开，对于较大的系统，这种效果是巨大的，因为标准方法可能低估了血小板的通量，从而损害了当前血小板功能测试的有效性。
The transport of platelets in blood is commonly assumed to obey an advection-diffusion equation. Here we propose a disruptive view, by showing that the random part of their velocity is governed by a fat-tailed probability distribution, usually referred to as a Lévy flight. Although for small spatio-temporal scales, it is hard to distinguish it from the generally accepted "red blood cell enhanced" Brownian motion, for larger systems this effect is dramatic as the standard approach may underestimate the flux of platelets by several orders of magnitude, compromising in particular the validity of current platelet function tests.
