论文标题
基于MRI的壁剪应力定量的参数顺序方法
Parametric Sequential Method for MRI-based Wall Shear Stress Quantification
论文作者
论文摘要
壁剪应力（WSS）已被认为是各种心血管疾病中的潜在生物标志物，可以从相对比磁共振成像（PC-MRI）速度测量中估算。我们为基于MRI的WSS定量提供了一种新的参数顺序方法，该方法由几何标识和随后的速度场近似。新方法在湍流固定流量和幻影中的生理脉冲流中进行了良好控制的高分辨率测量验证。使用三名志愿者的上升主动脉的2D PC-MRI数据证明了对体内的基本适用性。
Wall shear stress (WSS) has been suggested as a potential biomarker in various cardiovascular diseases and it can be estimated from phase-contrast Magnetic Resonance Imaging (PC-MRI) velocity measurements. We present a new parametric sequential method for MRI-based WSS quantification consisting of a geometry identification and a subsequent approximation of the velocity field. The new method was validated on well controlled, high resolution in vitro measurements of turbulent stationary flows and physiological pulsatile flows in phantoms. Basic applicability to in vivo was demonstrated using 2D PC-MRI data of the ascending aorta of three volunteers.
