论文标题
试验器：实时映射和浏览医学证据
Trialstreamer: Mapping and Browsing Medical Evidence in Real-Time
论文作者
论文摘要
我们介绍了试验播放器，这是一个临床试验报告的活着数据库。在这里，我们主要描述证据提取成分；这从生物医学摘要中提取了临床医生在评估文献以及这些信息之间需要的关键信息。具体而言，系统提取了试验参与者的描述，在每个臂（干预措施）中比较的治疗方法以及测量结果。然后，该系统试图通过确定其与已确定的试验结果指标的关系来推断哪些干预措施的效果最好。除了汇总个人试验外，这些提取的数据元素还允许在许多关于同一主题的试验中自动综合结果。我们将系统规模应用于MEDLINE索引的所有随机对照试验的报告，从而为自动生成的证据图提供动力，这些报告提供了对不同干预措施的疗效的全球视图，结合了所有相关临床试验的数据的功效。我们将所有代码和模型与Web界面的演示一起免费提供。
We introduce Trialstreamer, a living database of clinical trial reports. Here we mainly describe the evidence extraction component; this extracts from biomedical abstracts key pieces of information that clinicians need when appraising the literature, and also the relations between these. Specifically, the system extracts descriptions of trial participants, the treatments compared in each arm (the interventions), and which outcomes were measured. The system then attempts to infer which interventions were reported to work best by determining their relationship with identified trial outcome measures. In addition to summarizing individual trials, these extracted data elements allow automatic synthesis of results across many trials on the same topic. We apply the system at scale to all reports of randomized controlled trials indexed in MEDLINE, powering the automatic generation of evidence maps, which provide a global view of the efficacy of different interventions combining data from all relevant clinical trials on a topic. We make all code and models freely available alongside a demonstration of the web interface.
