论文标题
将血液透析(HD)膜转化为体外膜氧合(ECMO)机器
Converting Hemodialysis (HD) membranes to Extracorporeal Membrane Oxygenation (ECMO) machines
论文作者
论文摘要
诸如COVID-19之类的危机可能会对肺部受损的稀有血液氧合膜机产生巨大的未满足需求:体外膜氧合(ECMO)机器。同时,使用膜补充失败肾脏的血液透析(HD)机器非常普遍且广泛,其数量级比ECMO机器的可用级数更高。这项简短的研究检查了HD的膜是否可以用于血液氧合(ECMO)。为此,它考虑了在微尺度水平上的传质,并计算出宏观尺度水平,例如血液抽水率和O2供应压力。总体而言,虽然从技术上讲可能是可能的,但较差的气体运输可能需要一名患者的多个HD膜。
Crises like COVID-19 can create a massive unmet demand for rare blood oxygenation membrane machines for impaired lungs: Extracorporeal Membrane Oxygenation (ECMO) machines. Meanwhile, Hemodialysis (HD) machines, which use membranes to supplement failing kidneys, are extremely common and widespread, with orders of magnitude more available than for ECMO machines. This short study examines whether the membranes for HD can be modified for use in blood oxygenation (ECMO). To do so, it considers mass transfer at the micro-scale level, and calculations for the macro-scale level such as blood pumping rates and O2 supply pressure. Overall, while this conversion may technically be possible, poor gas transport likely requires multiple HD membranes for one patient.