论文标题

关键炎症介质和肺炎药物干预措施的功效膨胀的covid-19:一项Invivo数学建模研究

Crucial Inflammatory Mediators and Efficacy of Drug Interventions in Pneumonia Inflated COVID-19: An Invivo Mathematical Modelling Study

论文作者

Chhetri, Bishal, Vamsi, D. K. K., Bhagat, Vijay M., S., Ananth V., Prakash, Bhanu, Mandale, Roshan, Muthusamy, Swapna, Sanjeevi, Carani B

论文摘要

WHO WHO宣布了SARS-COV-2导致Covid-19引起的疾病。目前,超过210个国家和地区受到影响。仔细,精心设计的药物和疫苗以全部消除这种病毒似乎是小时的需要。在这种情况下,Invivo数学建模研究可能对理解药物干预的功效非常有帮助。这些研究还可以帮助了解关键炎症介质的作用以及免疫反应对这种新型冠状病毒的行为。在本文中,我们研究了Covid-19的Invivo动态。此处获得的结果与COVID-19的一些临床发现有关。这项涉及COVID-19的关键生物标志物的Intivo建模研究是第一个此类生物标志物,从此获得的结果可能对在该领域工作的研究人员,流行病学家,临床医生,临床医生和医生有帮助。

The virus SARS-COV-2 caused disease COVID-19 has been declared a pandemic by WHO. Currently, over 210 countries and territories have been affected. Careful, well-designed drugs and vaccine for the total elimination of this virus seem to be the need of the hour. In this context, the invivo mathematical modelling studies can be extremely helpful in understanding the efficacy of the drug interventions. These studies can also help understand the role of the crucial inflammatory mediators and the behaviour of immune response towards this novel coronavirus. Motivated by these facts, in this paper, we study the invivo dynamics of Covid-19. The results obtained here are inline with some of the clinical findings for Covid-19. This invivo modelling study involving the crucial biomarkers of Covid-19 is the first of its kind and the results obtained from this can be helpful to researchers, epidemiologists, clinicians and doctors who are working in this field.

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