论文标题

在神经脉冲传播的物理背景上:热量和能量

On physical background of nerve pulse propagation: heat and energy

论文作者

Engelbrecht, Jüri, Tamm, Kert, Peets, Tanel

论文摘要

最近的研究揭示了轴突中神经信号的复杂结构。除了电信号外,在许多实验研究中还检测到了机械和热效应。在本文中,在作者先前得出的一般模型的框架内分析了热产生的数学模型。热产生的主要机制似乎是焦耳加热和内部和放热反应。内部变量的概念允许对这些反应的典型热放松建模。根据负责出现信号组件的物理机制分析整个信号的一般能量平衡。列出了一些开放问题以进行进一步研究。

Recent studies have revealed the complex structure of nerve signals in axons. Besides the electrical signal, mechanical and thermal effects are also detected in many experimental studies. In this paper, the mathematical models of heat generation are analysed within the framework of a general model derived earlier by the authors. The main mechanisms of the heat generation are seemingly the Joule heating and endo- and exothermic reactions. The concept of internal variables permits to model the heat relaxation typical to these reactions. The general energy balance of the whole signal is analysed based on physical mechanisms responsible for emerging the components of a signal. Some open questions are listed for further studies.

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