学术文献库

Infectious diseases are still a major global burden for modern society causing 13 million deaths annually. One way to reduce the morbidity and mortality rates from infectious diseases is through preventative or targeted vaccinations. Current vaccination strategies, however, rely on the highly specific individual contact information that is difficult and costly to obtain, in order to identify influential spreading individuals. Current approaches also focus only on direct contacts between individuals for spreading, and disregard indirect transmission where a pathogen can spread between one infected individual and one susceptible individual that visit the same location within a short time-frame without meeting. This paper presents a novel vaccination strategy that relies on coarse-grained contact information, both direct and indirect, that can be easily and efficiently collected. Rather than tracking exact contact degrees of individuals, our strategy uses the types of places people visit to estimate a range of contact degrees for individuals, considering both direct and indirect contacts. We conduct extensive simulations to evaluate the performance of our strategy in comparison to the state of the art's vaccination strategies. Results show that our strategy achieves comparable performance to the oracle approach and outperforms all existing strategies when considering indirect links.