论文标题
COVID-19爆发的流行风险评估的新方法
A Novel Methodology for Epidemic Risk Assessment of COVID-19 outbreak
论文作者
论文摘要
我们提出了一个新型的数据驱动框架,用于评估地理区域的A-Priori流行风险并确定一个国家内的高风险区域。我们的风险指数是由三个不同组成部分的函数评估的:该疾病的危害,该地区的暴露及其居民的脆弱性。作为应用程序,我们讨论了意大利Covid-19-19的案例。我们通过使用有关空气污染,人类流动性,冬季温度,住房浓度,医疗保健密度,人口规模和年龄的可用历史数据来表征二十个意大利地区的每个地区。我们发现,在意大利中部和南部,一些北部地区的流行风险更高。相应的风险指数显示了与被感染人数,重症监护患者和已故患者的可用官方数据的相关性,并可以帮助解释为什么诸如伦巴第,艾米利亚 - 罗马尼亚(Emilia-Romagna),皮耶蒙特(Piemonte)和威尼托(Veneto)之类的地区遭受的痛苦远比全国其他地区高得多。尽管COVID-19爆发在北部(Lombardia)和意大利中部(拉齐奥)几乎同时开始,当时第一次病例在2020年初进行了正式认证,但该疾病在流行病风险较高的地区中的传播速度更快,后果更大。我们的框架可以扩展和测试其他流行病数据,例如季节性流感的流行数据,并应用于其他国家。我们还提出了与我们的方法相关的政策模型,这可能有助于决策者做出明智的决定。
We propose a novel data-driven framework for assessing the a-priori epidemic risk of a geographical area and for identifying high-risk areas within a country. Our risk index is evaluated as a function of three different components: the hazard of the disease, the exposure of the area and the vulnerability of its inhabitants. As an application, we discuss the case of COVID-19 outbreak in Italy. We characterize each of the twenty Italian regions by using available historical data on air pollution, human mobility, winter temperature, housing concentration, health care density, population size and age. We find that the epidemic risk is higher in some of the Northern regions with respect to Central and Southern Italy. The corresponding risk index shows correlations with the available official data on the number of infected individuals, patients in intensive care and deceased patients, and can help explaining why regions such as Lombardia, Emilia-Romagna, Piemonte and Veneto have suffered much more than the rest of the country. Although the COVID-19 outbreak started in both North (Lombardia) and Central Italy (Lazio) almost at the same time, when the first cases were officially certified at the beginning of 2020, the disease has spread faster and with heavier consequences in regions with higher epidemic risk. Our framework can be extended and tested on other epidemic data, such as those on seasonal flu, and applied to other countries. We also present a policy model connected with our methodology, which might help policy-makers to take informed decisions.