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Despite the powerful feature extraction capability of Convolutional Neural Networks, there are still some challenges in saliency detection. In this paper, we focus on two aspects of challenges: i) Since salient objects appear in various sizes, using single-scale convolution would not capture the right size. Moreover, using multi-scale convolutions without considering their importance may confuse the model. ii) Employing multi-level features helps the model use both local and global context. However, treating all features equally results in information redundancy. Therefore, there needs to be a mechanism to intelligently select which features in different levels are useful. To address the first challenge, we propose a Multi-scale Attention Guided Module. This module not only extracts multi-scale features effectively but also gives more attention to more discriminative feature maps corresponding to the scale of the salient object. To address the second challenge, we propose an Attention-based Multi-level Integrator Module to give the model the ability to assign different weights to multi-level feature maps. Furthermore, our Sharpening Loss function guides our network to output saliency maps with higher certainty and less blurry salient objects, and it has far better performance than the Cross-entropy loss. For the first time, we adopt four different backbones to show the generalization of our method. Experiments on five challenging datasets prove that our method achieves the state-of-the-art performance. Our approach is fast as well and can run at a real-time speed.