论文标题
自组织的网络,自组织网络的发展,达尔尼蛋白环的进化,茎和茎头
Self-Organized Networks, Darwinian Evolution of Self-Organized Networks, Darwinian Evolution of Dynein Rings, Stalks and Stalk Heads
论文作者
论文摘要
细胞骨架是基于聚合蛋白,肌动蛋白,微管蛋白的自组织网络,并由运动蛋白(例如肌球蛋白,驱动蛋白和动力蛋白)驱动。他们积极的达尔文进化使他们能够接近优化的功能自组织的批判性。 Dynein具有三个独特的标题亚基,但是这些单元如何连接到分子电动机的功能是神秘的。动力蛋白通过两个盘绕的线圈茎和一个茎头结合微管蛋白。 ATP在1500氨基酸的环上提供了用于改变头部结合和推动沿微管蛋白的货物的能量。
Cytoskeletons are self organized networks based on polymerized proteins, actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian evolution enables them to approach optimized functionality self organized criticality. Dynein has three distinct titled subunits, but how these units connect to function as a molecular motor is mysterious. Dynein binds to tubulin through two coiled coil stalks and a stalk head. The energy used to alter the head binding and propel cargo along tubulin is supplied by ATP at a ring 1500 amino acids away.