论文标题
多变量荟萃分析中研究中协方差的估计
Estimation of within-study covariances in multivariate meta-analysis
论文作者
论文摘要
在将研究结合在一起时，多元荟萃分析可以适应多种结果和多个治疗组的多种情况。效应大小之间的研究内相关性通常是在多变量荟萃分析中知道的，而实际上并不总是知道。在本文中，我们提出了一种通用方法，以近似多元荟萃分析中效应大小的研究中的协方差，并将此方法应用于具有多个结果的情景，并分别具有多个治疗组的结果。
Multivariate meta-analysis can be adapted to a wide range of situations for multiple outcomes and multiple treatment groups when combining studies together. The within-study correlation between effect sizes is often assumed known in multivariate meta-analysis while it is not always known practically. In this paper, we propose a generic method to approximate the within-study covariance for effect sizes in multivariate meta-analysis and apply this method to the scenarios with multiple outcomes and one outcome with multiple treatment groups respectively.
