论文标题
癌症治疗的抗氧化剂的新兴类别：临床和实验研究的综述
Emerging classes of antioxidant to cancer therapy: a review of clinical and experimental studies
论文作者
论文摘要
这篇评论主要关注抗氧化剂与癌症治疗之间的关系。据报道，抗氧化剂在减少自由基物种方面起着重要作用。自由基通常会导致氧化损伤，这是衰老过程中的一个常见因素，也是形成的重要因素，并且主要疾病特别是癌症。虽然，自从最近几十年以来，几种属于天然和合成起源的抗氧化剂已在针对氧化应激的临床试验中进行了测试，但是这些临床试验最终会产生不良影响。这篇综述还遵守了最新的氧化应激发现，突出了自由种族生产以及其在细胞和分子水平上相关的氧化损伤，以及新的和现有的自然自由基清除剂的新自然和合成类别及其相关的临床试验。
This review mainly focuses on the relation between antioxidants with cancer therapy. Antioxidants have been reported to play an essential role to reduce free radical species. Free radicals commonly cause oxidative damage which is a common factor in the aging process, and also the vital factor of formation, and development of major disease specially cancer. Although, since last many decades several antioxidants belong to natural and synthetic origin have been tested in clinical trials against oxidative stress, however these clinical trials end up with undesirable effects. This review also complied with the most recent findings of oxidative stress, highlighting of free racial production, and its related oxidative damage at cellular and molecular level, with the new and existing natural and synthetic classes of free radical scavenger and their related clinical trials.
