论文标题
调节干扰素生产作为COVID-19治疗的潜在策略
Regulation of interferon production as a potential strategy for COVID-19 treatment
论文作者
论文摘要
调节细胞因子产生的上游可能是治疗Covid-19的有前途的策略。我们建议更多地关注Covid-19的IFN-I产量失调，并考虑CGA，ALK和Sting作为预防细胞因子风暴的潜在治疗靶标。经过认可的药物（如苏拉明和ALK抑制剂）值得进行临床试验。
Regulating the upstream of the cytokines production could be a promising strategy to the treatment of COVID-19. We suggest to pay more attention to the dysregulated IFN-I production in COVID-19 and to considerate cGAS, ALK and STING as potential therapeutic targets preventing cytokine storm. Approved drugs like suramin and ALK inhibitors are worthy of clinical trials.
