论文标题
在热治疗期间监测组织温度的高温纤维辐射温度计的开发
Development of Hyperthermia Measurable Fiber Radiometric Thermometer for Monitoring Tissue Temperature during Thermo-therapy
论文作者
论文摘要
摘要：在热疗期间，温度监测非常重要。纤维温度传感器是优选的，因为它们具有灵活性和对电磁干扰的不利性。尽管已经开发了许多类型的光纤传感器，但它重新采用了临床采用的挑战。在这里，我们报告了使用低成本扩展INGAAS检测器的基于二氧化硅纤维的辐射温度计，以检测1.7UM至2.4 um之间的黑色体辐射。这款基于二氧化硅纤维的温度计首次能够将温度降低到35°C，使其适合于与激光间隙热疗法中使用的当前二氧化硅纤维导管无缝整合，以在手术过程中监测高温。通过体内和体内组织研究证明了跟踪组织温度变化的可行性，能力和敏感性。该技术有望在进一步提高信号与噪声比之后被转化为诊所。
ABSTRACT: Temperature monitoring is extremely im-portant during thermotherapy. Fiber-optic temperature sensors are preferred because of their flexibility and im-munity to electromagnetic interference. Although many types of fiber-optic sensors have been developed, it re-mains challenging for clinically adopting them. Here, we report a silica fiber-based radiometric thermometer using a low-cost extended InGaAs detector to detect black body radiation between 1.7um to 2.4 um. For the first time, this silica fiber-based thermometer is capable of measuring temperature down to 35°C, making it suitable for seamless integration with current silica fiber catheters used in laser interstitial thermotherapy to monitor hyperthermia during a surgery. The feasibility, capability, and sensitivity of track-ing tissue temperature variation were proved through ex vivo and in vivo tissue studies. The technology is promising for being translated into clinics after further improving the signal to noise ratio.
