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Addressing a quest by Gupta et al. [ICALP'14], we provide a first, comprehensive study of finding a short s-t path in the multistage graph model, referred to as the Multistage s-t Path problem. Herein, given a sequence of graphs over the same vertex set but changing edge sets, the task is to find short s-t paths in each graph ("snapshot") such that in the found path sequence the consecutive s-t paths are "similar". We measure similarity by the size of the symmetric difference of either the vertex set (vertex-similarity) or the edge set (edge-similarity) of any two consecutive paths. We prove that these two variants of Multistage s-t Path are already NP-hard for an input sequence of only two graphs and maximum vertex degree four. Motivated by this fact and natural applications of this scenario e.g. in traffic route planning, we perform a parameterized complexity analysis. Among other results, for both variants, vertex- and edge-similarity, we prove parameterized hardness (W[1]-hardness) regarding the parameter path length (solution size) for both variants, vertex- and edge-similarity. As a further conceptual study, we then modify the multistage model by asking for dissimilar consecutive paths. As one of the main technical results (employing so-called representative sets known from non-temporal settings), we prove that dissimilarity allows for fixed-parameter tractability for the parameter solution size, contrasting our W[1]-hardness proof of the corresponding similarity case. We also provide partially positive results concerning efficient and effective data reduction (kernelization).