论文标题
活性离子传输的热力学模型
A Thermodynamic Model for Active Ion Transport
论文作者
论文摘要
活性离子运输对于活细胞维护和常规的内部和外部环境至关重要。众所周知，腺苷5'-三磷酸（ATP）是一种通用能源，可将键能施加泵的能量来克服离子浓度梯度。在这项研究中，我们引入了一种新型的活性离子传输热力学模型，该模型允许泵充当“麦克斯韦的恶魔”，并且还符合热力学的第二定律。针对梯度的运输是由热力学波动引起的，并在ATP流中记录了信息。此外，对在红细胞幽灵系统中进行的NA-K ATPase进行的详尽实验进行了审查以验证该模型，所有结果都可以支持有关恶魔泵的工作机理的可解决理论。我们的发现表明，ATP作为信息载体而不是能源货币的作用。 The high-energy phosphate bonds can improve the efficiency of information recording in relevance to ion transport and may mainly convert to heat.
Active ion transport is very critical for living cells to maintain and regular internal and external environment. It is known that adenosine 5'-triphosphate (ATP) is a general energy source that applies bond energy for pumps to overcome ion concentration gradient. In this study, we introduce a novel thermodynamic model for active ion transport, which allows the pump to act as a 'Maxwell's demon', and also conforms to the second law of thermodynamics. Transport against the gradient is caused by the thermodynamic fluctuation with information recording in ATP stream. Besides, exhaustive experiments about Na-K ATPase performed in the red cell ghost system are reviewed to verify this model, and all the results can support the solvable theory about the working mechanism of demon pumps. Our findings indicate the possible role of ATP as an information carrier but not energy currency. The high-energy phosphate bonds can improve the efficiency of information recording in relevance to ion transport and may mainly convert to heat.
